Back to the Teratology Society home page
Meetings
Future TS Meetings
Past TS Meetings
Society Awards
Meetings of Interest to TS Members

Back to the Teratology Society home page Contact the Teratology Society

2004 Meeting Highlights

Vancouver, British Columbia, Canada
June 26 - July 1, 2004

Registration Information

Vancouver Convention and Visitors Bureau

Program on this page
(Updated 13-APR-2004)

Download Program PDF
(Updated 09-APR-2004)

Instructions for Platform Presenters

Continuing Education Course

Instructions for Poster Presenters

Exhibitors
Sustaining Members
Sponsors

Registration Information

DATES TO REMEMBER:

February 13, 2004 Abstract Submission Deadline
May 28, 2004 Advance Registration Deadline

May 25, 2004 Hotel Reservation Deadline
June 1, 2004 Pre-Registration Deadline



Program (Updated 13-APR-2004)

top

 

Quick Index (click the day at top to go there) 

Saturday,
June 26
Sunday,
June 27
Monday,
June 28
Tuesday,
June 29
Wednesday,
June 30
Thursday,
July 1
           
Education Course Education Course continued

WARKANY LECTURE
Carl L. Keen

Mini course: Epidemiology: The Basics SPER/TS JOINT SYMPOSIUM - Epidemiology of Miscarriage WILEY-LISS SYMPOSIUM - The Role of Neural Crest Cells
  SYMPOSIUM - Assisted Reproductive Technology (ART) and Reproductive Problems Wilson Publication Award Presentation and Address PUBLIC AFFAIRS COMMITTEE SYMPOSIUM NBTS/OTIS/TS JOINT SYMPOSIUM
Birth Defects and Other Adverse Pregnancy Outcomes Due to Maternal Obesity
PLATFORM SESSION I - Mechanisms of Abnormal Development  
 

MATERNAL-FETAL MEDICINE
Teratogenic Implication of Maternal Disease
and its Treatment

SPECIAL LECTURE
Fetal Determinants of Long Term Health
Speaker: Judith Hall
Concurrent Symposium I - NBTS/TS JOINT SYMPOSIUM
Neurobehavioral Outcomes of Common Exposures
PLATFORM SESSION II - Clinical Teratology and Epidemiology  
  National Children's Study Update Student Plenary Session and Posters and Exhibits open

Concurrent Symposium II - Pharmacokinetics and Metabolism in Pregnancy and Lactation - Consideration for Maternal Therapy and Fetal and Neonatal Risk

PLATFORM SESSION III - Title to be Determined  
    Public Affairs Committee Workshop (Joint session with NTBS/OTIS/ TS)

Joint Teratology/
NBTS Poster Session II

Business Meeting  
    CONCURRENT SYMPOSIUM I
TS/OTIS JOINT SESSION
Teratogen Update
  Banquet Reception  
    CONCURRENT SYMPOSIUM II
Computational Systems Biology and Implications for Developmental Toxicology: From Molecules to Systems
  Wilson and Fraser Banquet  
   

Issues Forum / Editor Reports

     
    JOINT TS/NBTS/OTIS POSTER SESSION I      
    MARTA/MTA STUDENT CAREER EVENT      

 

 

 

 

Saturday, June 26
9:00 AM - 12:00 NOON COUNCIL 1A MEETING
11:30 AM - 5:00 PM REGISTRATION
1:00 PM - 5:00 PM EDUCATION COURSE PART 1
(separate registration required)
Signaling and Tissue Interactions in Organ-System Development

Organized by the Education Committee, Michael G. Narotsky, Chairperson
Sponsored by DuPont Haskell Laboratory and Endo Pharmaceuticals, Inc.
Coursebooks provided by CTBR


1:00 PM – 1:10 PM Welcome – Rochelle W. Tyl, President,
Teratology Society

1:10 PM – 1:15 PM Introduction
Speaker: Michael G. Narotsky, U.S. EPA

1:15 PM – 2:00 PM Overview of Signaling and Development
Speaker: Henk Roelink, University of Washington

2:00 PM – 2:45 PM Patterning
Speaker: Claudia Kappen, University of Nebraska Medical Center

2:45 PM – 3:00 PM Break

3:00 PM – 3:45 PM Cellular, Molecular and Genetic Approaches to Study Cell Migration In Vivo
Speaker: Vanessa Auld, University of British Columbia

3:45 PM – 4:30 PM Signaling and Tissue Interactions in Morphogenesis
Speaker: Barbara Abbott, U.S. EPA

 

5:00 PM - 9:00 PM

COUNCIL 1B MEETING (Committee Reports)

 

Sunday, June 27

top

7:30 AM - 8:15 PM EDUCATION COURSE CONTINENTAL BREAKFAST
8:00 AM - 5:00 PM REGISTRATION
8:15 AM - 11:30 AM EDUCATION COURSE PART II: (CONTINUED FROM SATURDAY)

Signaling Pathways and Tissue Interactions in Organ-System Development

8:15 AM – 9:00 AM Development of Bone and Cartilage
Speaker: Rocky Tuan, NIH/NIAMS

9:00 AM – 9:45 AM Heart Development
Speaker: Ida Smoak, North Carolina State University

9:45 AM – 10:00 AM Break

10:00 AM – 10:45 AM Patterning of the Gastrointestinal Tract and Derivatives
Speaker: Drucilla Jane Roberts, Harvard Medical School

10:45 AM – 11:30 AM Signaling in Genitourinary Development
Speaker: H. Scott Stadler, Oregon Health Sciences University

1:00 PM - 4:00 PM MARCH OF DIMES SYMPOSIUM

RNA Interference (RNAi) Approaches to the Study of Normal and Abnormal Development
Organized by Philip E. Mirkes, University of Washington;
Jan Friedman, University of British Columbia, Vancouver; and
Richard Finnell, Texas A&M University System Health Science Center

Sponsored by March of Dimes Birth Defects Foundation Grant No. 4-FY03-138

1:00 PM – 1:05 PM Introduction
Speaker: Philip E. Mirkes, University of Washington

1:05 PM – 1:40 PM S1 Enabling Developments in siRNA-Mediated Gene Silencing
Speaker: Steve Daniel, Dharmacon RNA Technologies, Inc.

1:40 PM – 2:20 PM S2 RNAi in C. Elegans
Speaker: TBA

2:20 PM – 2:40 PM Break

2:40 PM – 3:20 PM S3 MicroRNA Regulators of Cell Death in Development
Speaker: Bruce Hay, California Institute of Technology

3:20 PM – 4:00 PM S4 Mus Musculus, RNAi and Development
Speaker: Janet Rossant, Samuel Lunenfeld Research Institute

4:15 PM - 6:00 PM MATERNAL-FETAL MEDICINE

Teratogenic Implication of Maternal Disease and its Treatment
This session will address from the perinatologist’s perspective, two common maternal conditions that may have significant impact on fetal development. The presentations will focus on the effect on fetal development of treatment of the maternal disease as well as the disease itself.
Moderator: Andy Hull, University of California, San Diego

4:15 PM – 4:25 PM Introduction
Speaker: Andy Hull, University of California, San Diego

4:25 PM – 5:05 PM S5 Maternal Diabetes
Speaker: Tom Moore, University of California, San Diego

5:05 PM – 5:45 PM S6 Hypertensive Disorders and Pregnancy
Speaker: John Kingdom, Mount Sinai Hospital

5:45 PM – 6:00 PM Discussion

6:00 PM - 6:15 PM

NATIONAL CHILDREN'S STUDY UPDATE
Speaker: Donald Mattison, NICHD

6:15 PM - 7:45 PM WELCOMING RECEPTION AND EXHIBITS OPEN
Sponsored by Bristol-Myers Squibb, MPI Research and RTI International

 

Monday, June 28

top

7:00 AM - 8:15 AM BDR-B EDITORIAL MEETING
8:00 AM - 5:00 PM REGISTRATION
8:00 AM - 8:10 AM PRESIDENT'S WELCOME
Rochelle W. Tyl
8:10 AM - 9:00 AM

THE JOSEF WARKANY LECTURE:

Speaker: Carl L. Keen, University of California, Davis

9:00 AM - 9:45 AM

The James G. Wilson Publication Award Presentation and Address
Neural and Orofacial Defects in Folbp 1 Knockout Mice
Speaker: Richard H. Finnell, Texas A&M University System Health Science Center

10:00 AM - 11:00 AM

SPECIAL LECTURE
Fetal Determinants of Long Term Health
Speaker: Judith Hall, University of British Columbia, Vancouver

11:00 AM - 12:30 PM

Student Plenary Session

11:00 AM – 11:15 AM

The Effect of 2-agonists and Inhaled Corticosteroids Used to Treat Asthma in Pregnancy on Fetal Growth.
L.N. Bakhireva, K.L. Jones, D.L. Johnson, G.R. Macaraeg, C.D. Chambers. Department of Pediatrics, University of California, San Diego, La Jolla, CA, United States.

11:15 AM – 11:30 AM

Cellular Anomalies Underlying Retinoid-Induced Phocomelia.
J. Zhou, D.M. Kochhar. Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, United States.

11:30 AM – 11:45 AM

Evidence of Increased Birth Defects in the Offspring of Women Exposed to Valproate during Pregnancy: Findings from the AED Pregnancy Registry.
R.M. Alsdorf1, D.F. Wyszynski1, L.B. Holmes2, M. Nambisan3. 1Boston University School of Medicine, Department of Medicine, Boston, MA, United States, 2Massachusetts General Hospital, Pediatric Service, Boston, MA, United States, 3Harvard Medical School, Department of Pediatrics, Boston, MA, United States.

11:45 AM – 12:00 PM

Teratogen Update: Potential Risks of Angiotensin II Receptor Antagonists during Pregnancy.
S. Alwan1, J.E. Polifka2, J.M. Friedman1. 1Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada, 2Department of Pediatrics, University of Washington, Seattle, Washington, United States.

12:00 PM – 12:15 PM

The Role of Retinoic Acid Receptors Alpha 1 and Gamma in Retinoid-Induced Limb Dysmorphogenesis.
E. Galdones1, D. Lohnes2, B.F. Hales1. 1McGill University, Department of Pharmacology & Therapeutics, Montreal, QC, Canada, 2Institut de Recherches Cliniques de Montreal, Montreal, QC, Canada.

12:15 PM – 12:30 PM

Activator Protein 1 (AP-1) DNA Binding Activity Is Induced in the Mouse Embryo during Organogenesis by Hydroxyurea (HU).
J. Yan, B.F. Hales. McGill University, Department of Pharmacology & Therapeutics, Montreal, QC, Canada.
12:30 PM - 7:30 PM POSTERS AND EXHIBITS OPEN
1:00 PM - 4:00 PM CONCURRENT SYMPOSIUM I
TS/OTIS JOINT SESSION

Teratogen Update
Organized by Robert Brent, Alfred I. duPont Hospital for Children

1:00 PM - 1:05 PM

Introduction
Speaker: Robert Brent, Alfred I. duPont Hospital for Children

1:05 PM - 1:35 PM

Genetic Polymorphisms: Impact on the Risk of FAS
Speaker: Ting-Kai Li, National Institute on Alcohol Abuse and Alcoholism

1:35 PM - 2:05 PM

Update on the Risk of New Anticonvulsants
Speaker: Lewis B. Holmes, Massachusetts General Hospital for Children

2:05 PM - 2:35 PM

Pesticides: The Risk of Birth Defects and Cancer
Speaker: Rochelle W. Tyl, RTI International

2:35 PM - 2:50 PM

Break

2:50 PM - 3:20 PM

Trimethoprim Teratogenicity
Speaker: Sonia Hernandez-Diaz, Slone Epidemiology Center, Boston University

3:20 PM - 3:50 PM

Trichloroethyelene (TCE) and Cardiac Teratogenicity
Speaker: Robert Brent, Alfred I. duPont Hospital for Children

3:50 PM - 4:00 PM

Discussion

 

1:00 PM - 4:00 PM CONCURRENT SYMPOSIUM II

Computational Systems Biology and Implications for Developmental Toxicology: From Molecules to Systems
Organized by Robert Kavlock and Elaine Francis, U.S. EPA

Sponsored by U.S. EPA

1:00 PM – 1:10 PM

Introduction
Speaker: Robert Kavlock, U.S. EPA

1:10 PM – 1:40 PM

Computational Approaches for Predicting the Toxicological Effects of Xenobiotic Chemicals
Speaker: William J. Welsh, RW Johnson Medical School

1:40 PM – 2:10 PM

Towards Understanding Development: Building a Model of the Early Sea Urchin Embryo
Speaker: C. Titus Brown, California Institute of Technology

2:10 PM – 2:40 PM

Understanding Pathways of Toxicity: Making Sense of Changing Signals
Speaker: Sid Hunter, U.S. EPA

2:40 PM ­ 3:00 PM

Break

3:00 PM ­ 3:30 PM

Network Models of EGF Receptor Signaling during Cell Organization and Differentiation
Speaker: H. Steven Wiley, Pacific Northwest National Laboratory

3:30 PM ­ 4:00 PM

Birth Defects Systems Manager and Teratology Analyzer: A Beginning
Speaker: Thomas Knudsen, University of Louisville
4:00 PM - 5:00 PM ISSUES FORUM/EDITOR REPORTS
5:00 PM - 7:30 PM JOINT TS/NBTS/OTIS POSTER SESSION I
7:30 PM - 10:30 PM MARTA/MTA STUDENT CAREER EVENT

 

Tuesday, June 29

top

7:00 AM - 8:15 AM BDR-A EDITORIAL MEETING
7:30 AM - 8:00 AM MINI COURSE ATTENDEE CONTINENTAL BREAKFAST
8:00 AM - 5:00 PM REGISTRATION
8:00 AM - 9:30 AM MINI COURSE
(Separate Registration Required)

Epidemiology: the Basics
Organized by the Education Committee, Michael G. Narotsky, Chairperson
Coursebooks provided by CTBR

8:00 AM ­ 8:45 AM

Clinical Epidemiology
Speaker: Christina Chambers, University of California, San Diego

8:45 AM ­ 9:30 AM

Current Issues in Molecular Epidemiology
Speaker: Andrew Olshan, University of North Carolina
9:30 AM - 12:00 NOON PUBLIC AFFAIRS COMMITTEE SYMPOSIUM
(NBTS/OTIS/TS JOINT SYMPOSIUM)

Birth Defects and Other Adverse Pregnancy Outcomes Due to Maternal Obesity
Organized by James Mills, NICHD; Thomas Flynn, U.S. FDA; and Christina Chambers, University of California, San Diego
Sponsored by the Teratology Society and NBTS

9:30 AM ­ 9:40 AM

Introduction
Speaker: Thomas Flynn, U.S. FDA

9:40 AM ­ 10:05 AM

Neural Tube Defects & Other Birth Defects Associated with Maternal Obesity—Risks, Ethnic Variability, and Folic Acid Prevention
Speaker: Gary Shaw, California Birth Defects Monitoring Program

10:05 AM ­ 10:30 AM

Maternal Obesity and Adverse Obstetrical Outcome
Speaker: Joel Ray, University of Toronto

10:30 AM ­ 10:55 AM

Break

10:55 AM ­ 11:20 AM

Causes and Prevention of Maternal Obesity—Genetics, Regulation of Appetite, Suppression of Appetite, Strategies for Weight Loss
Speaker: David Cummings, University of Washington

11:20 AM ­ 11:45 AM

The Epidemic of Obesity—National and International Policy and Strategic Approaches to Prevention
Speaker: William Dietz, Centers for Disease Control

11:45 AM ­ 12:00 PM

Closing Remarks
Speaker: James Mills, NICHD
12:00 PM - 1:00 PM 2005 PROGRAM COMMITTEE MEETING
12:30 PM - 7:30 PM POSTERS AND EXHIBITS OPEN
1:00 PM - 4:30 PM Concurrent Symposium I (NBTS/TS JOINT SYMPOSIUM)

Neurobehavioral Outcomes of Common Exposures
Organized by Sherry Ferguson, National Center for Toxicological Research, U.S. FDA; and Kenneth Lyons Jones, University of California, San Diego

1:00 PM ­ 1:10 PM

Introduction
Speaker: Sherry Ferguson, National Center for Toxicological Research, U.S. FDA

1:10 PM ­ 1:40 PM

Accutane
Speaker: Jane Adams, University of Massachusetts

1:40 PM ­ 2:10 PM

Cocaine
Speaker: Gale Richardson, University of Pittsburgh

2:10 PM ­ 2:40 PM

PCB
Speaker: Sandra Jacobson, Wayne State University

2:40 PM ­ 3:00 PM

Break

3:00 PM ­ 3:30 PM

Alcohol
Speaker: Claire D. Coles, Emory University School of Medicine

3:30 PM ­ 4:00 PM

Prozac
Speaker: Sarah Mattson, San Diego State University

4:00 PM ­ 4:30 PM

Phenobarbital
Speaker: Jane Adams, University of Massachusetts

1:00 PM - 4:30 PM

Concurrent Symposium II

Pharmacokinetics and Metabolism in Pregnancy and Lactation—Consideration for Maternal Therapy and Fetal and Neonatal Risk
Organized by Dana L. Shuey, Endo Pharmaceuticals, Inc.
Sponsored by Middle Atlantic Reproduction and Teratology Association and Midwest Teratology Association

1:00 PM ­ 1:10 PM

Introduction
Speaker: Dana L. Shuey, Endo Pharmaceuticals, Inc.

1:10 PM ­ 1:55 PM

Ontogeny of Human Drug-Metabolism
Speaker: Ronald Hines, Medical College of Wisconsin

1:55 PM ­ 2:40 PM

Metabolism and Drug Transporters in the Placenta
Speaker: William Slikker, Jr., National Center for Toxicology Research

2:40 PM ­ 3:00 PM

Break

3:00 PM ­ 3:45 PM

Treating the Mother—Protecting the Unborn: Toward Rational Drug Therapy in Pregnancy
Speaker: Gideon Koren, Hospital for Sick Children

3:45 PM ­ 4:30 PM

Transfer of Drugs and Chemicals into Human Milk: Rational Risk Assessment
Speaker: Shinya Ito, Hospital for Sick Children
5:00 PM - 7:30 PM Joint Teratology/NBTS Poster Session II

 

Wednesday, June 30

top

7:00 AM ­ 8:00 AM Public Affairs Committee Meeting
7:00 AM ­ 8:00 AM Publications Committee Meeting
8:00 AM - 5:00 PM
REGISTRATION
8:30 AM - 11:30 AM
SPER/TS JOINT SYMPOSIUM

Epidemiology of Miscarriage
Goal: Examine the methods and current knowledge regarding the causes of miscarriage derived from epidemiology, with consideration of corresponding toxicology, measurement challenges, and future prospects for improved study.
Organized by Christina Chambers, University of California,
San Diego; Martha M. Werler, Slone Epidemiology Center; and
David A. Savitz, University of North Carolina

8:30 AM ­ 8:40 AM

Introduction
Speaker: Martha M. Werler, Slone Epidemiology Center, Boston University

8:40 AM ­ 9:05 AM

Animal Models for Studying Miscarriage—Illustration with Study of Drinking Water Disinfection By-Products
Speaker: Michael G. Narotsky, U.S. EPA

9:05 AM ­ 9:30 AM

Genetic Causes of Miscarriage
Speaker: Wendy P. Robinson, University of British Columbia

9:30 AM ­ 10:00 AM

Warkany Tea

10:00 AM ­ 10:25 AM

Autoimmune Causes of Miscarriage
Speaker: Mary Stephenson, University of Chicago

10:25 AM ­ 10:50 AM

Epidemiologic Approaches to the Study of Early Miscarriage
Speaker: Germaine Buck, NICHD

10:50 AM ­ 11:15 AM

Epidemiologic Evidence on Causes of Miscarriages: Illustration with Ongoing Study of Drinking Water Disinfection By-Products
Speaker: David A. Savitz, University of North Carolina

11:15 AM ­ 11:45 PM

Closing Comments and Discussion
Speaker: Christina Chambers, University of California, San Diego
11:45 AM - 1:15 PM

PAST PRESIDENTS' LUNCHEON (by invitation only)

1:00 PM - 5:00 PM

PLATFORM SESSIONS

PLATFORM SESSION I
Mechanisms of Abnormal Development

1:00 PM ­ 1:15 PM

Laser Capture Microdissection and Gene Array Analysis of Palatal Epithelial and Mesenchymal Cells Exposed to TCDD.
B.D. Abbott, J.E. Schmid. Repro.Tox.Div., U.S. EPA, Research Triangle Park, NC, United States.

1:15 PM ­ 1:30 PM

Alterations in Biotin-Dependent Carboxylases in Fetal and Maternal Liver Induced by Biotin Deficiency.
D.K. Hansen1, S.L. Stratton2, W.M. Sealey2, D.M. Mock2. 1National Center for Toxicological Research, Division of Genetic and Reproductive Toxicology, Jefferson, AR, United States, 2University of Arkansas for Medical Sciences, Department of Biochemistry and Molecular Biology, Little Rock, AR, United States.

1:30 PM ­ 1:45 PM

The Progressive Effects of Heat Stress on Somitogenesis and Other Developing Tissues in the Rat.
K.E. Wheeler1, G.L. Kimmel2, T.W. Claggett3, C.A. Kimmel4. 1Orise Fellow U.S. FDA Center for Devices and Radiological Health, Rockville, MD, United States, 2Visiting Scientist, U.S. FDA, Rockville, MD, United States, 3Charles River Laboratories, Frederick, MD, United States, 4National Center for Environmental Assessment/ORD, U.S. EPA, Washington, DC, United States.

1:45 PM ­ 2:00 PM

Beneficial Effect of Folate in Two Genetic Models of Aberrant Skeletal Development.
C. Kappen, C. Kruger, C. Talmadge, J.M. Salbaum. University of Nebraska Medical Center, Department of Genetics, Cell Biology and Anatomy, Omaha, NE, United States.

2:00 PM ­ 2:15 PM

Intra Uterine Growth Restriction: A Unique Experimental Rat Model Combining Genetic and Environmental Causative Factors.
M. Avgil1, R.K. Miller2, A. Ornoy1. 1Hebrew University Hadassah Medical School, Jerusalem, Israel, 2School of Medicine and Dentistry, University of Rochester, Rochester, NY, United States.

2:15 PM ­ 2:30 PM

In Utero and Lactational Exposures to Low Dose PBDE 47 Cause Neurobehavior Disturbances in Rat Offspring.
S.N. Kuriyama, C.E. Talsness, I. Chahoud. Institute of Clinical Pharmacology and Toxicology, Charoté University Medical School Berlin, Campus Benjamin Franklin, Berlin, Germany.

2:30 PM ­ 2:45 PM

Altered Gene Expression of Mouse Embryo Cultures Exposed to Bromochloroacetic Acid.
E.D. Karoly1, J.E. Schmid2, M.R. Blanton2, E.S. Hunter III2. 1University of North Carolina at Chapel Hill, Curriculum in Toxicology, Chapel Hill, NC, United States, 2U.S. EPA, Reproductive Toxicology Division, Research Triagle Park, NC, United States.

2:45 PM ­ 3:00 PM

Phospholipase C Signaling in Ethanol-Induced Apoptosis during Early Embryo Development.
A. Garic-Stankovic1, M. Hernandez1, K.A. Kragtorp-Debelak1, D.R. Armant2, S.M. Smith1. 1Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, United States, 2Department of Obstetrics & Gynecology; Wayne State University, Detroit, MI, United States.

3:00 PM ­ 3:15 PM

Break

3:15 PM ­ 3:30 PM

Cell Death and Developmental Timing Are Critical Determinants of Facial Dysmorphology in the Chick Model of Prenatal Alcohol Exposure.
K.A. Kragtorp-Debelak, M. Moyers, A. Garic-Stankovic, S.M. Smith. Dept. Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, United States.

3:30 PM ­ 3:45 PM

Fumonisin, Folate, and Neural Tube Defects: Novel Mechanisms Involving TNF? Signaling and Redox Homeostasis.
J. Gelineau-Van Waes, L. Starr, J. Wilberding, F. Aleman, J. Maddox. Dept. Genetics, Cell Biology & Anatomy, University of Nebraska Medical Center, Omaha, NE, United States.

3:45 PM ­ 4:00 PM

The Role of Hypoxia-Inducible Factor-1 (HIF-1 Alpha) in Mouse Limbs Exposed to 4-Hydroperoxycyclophosphamide In Vitro.
C. Huang, B.F. Hales. McGill University, Department of Pharmacology & Therapeutics, Montreal, QC, Canada.

4:00 PM ­ 4:15 PM

Role of P53 in Regulation of Cell Death and Cell Survival in Teratogen Treated Day 9 Mouse Embryos.
S.A. Little, P.E. Mirkes. University of Washington, Department of Pediatrics, Seattle, WA, United States.

4:15 PM ­ 4:30 PM

Disruption of Heart Development by Trichloroethylene, a Common Groundwater Contaminant.
V.J. Drake1, S.L. Koprowski2, J.W. Lough2, S.M. Smith1. 1Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, United States, 2Department of Cell Biology, Anatomy and Neurobiology, Medical College of Wisconsin, Milwaukee, WI, United States.

4:30 PM ­ 4:45 PM

The Impact of Pax3 and Cystathionine Beta Synthase Mutations on Arsenic Induced Birth Defects.
E.K. Marshall1, A.F. Machado2, A.F. Elsaid3, M.D. Collins1. 1Univerity of California Los Angeles, Department of Environmental Health Sciences, Los Angeles, CA, United States, 2California State University, Northridge, Department of Environmental and Occupational Health, Northridge, CA, United States, 3University of California Los Angeles, Interdepartmental Program in Molecular Toxicology, Los Angeles, CA, United States.

4:45 PM ­ 5:00 PM

Amelioration of Vitamin A-Induced Malformations in the Mid-Organogenesis-Stage Mouse Limb Bud by A Retinoic Acid Receptor Alpha and Gamma Selective Antagonist.
S.E. Ali-Khan, B.F. Hales. McGill University, Department of Pharmacology and Therapeutics, Montreal, Quebec, Canada.

Platform Session II
Clinical Teratology and Epidemiology

1:00 PM ­ 1:15 PM

Hypospadias and Maternal Intake of Progestins and Oral Contraceptives.
S.L. Carmichael1, G.M. Shaw1, C. Laurent1, M. Croughan4, R.S. Olney2, E.J. Lammer3. 1MOD/CA Birth Defects Monitoring Program, Berkeley, CA, United States, 2CDC/NCBDDD, Atlanta, GA, United States, 3Children’s Hospital Research Institute, Oakland, CA, United States, 4UCSF, San Francisco, CA, United States.

1:15 PM ­ 1:30 PM

Ultrasound Imaging of the Neonatal Corpus Callosum Is Feasible and Useful.
F.L. Bookstein, A.P. Streissguth, C. Gleason, T. Lalani, P.D. Connor, T. Keener, K. Baldwin, W.D.K. Green. University of Washington, Fetal Alcohol and Drug Unit, Seattle, WA, United States.

1:30 PM ­ 1:45 PM

Autism and Ocular Malformations in CHARGE Association and Goldenhar Syndrome.
K. Strömland1, M. Miller2, M. Johansson3, S. Danielsson3, E. Billstedt3, C. Gillberg3, B.M. Ekman-Joelsson4. 1Pediatric Ophthalmology, Göteborg University, Göteborg, Sweden, 2Ophthalmology, University of Illinois, Chicago, United States, 3Child Neuropsychiatry, Göteborg University, Göteborg, Sweden, 4Pediatrics, Skövde, Sweden.

1:45 PM ­ 2:00 PM

Different Fetal Effects of Three Anticonvulsant Drugs on Skull and Face.
D. Doan2, L.A. Will2, L.B. Holmes1. 1Genetics & Teratology Unit, Pediatric Service, Massachussets General Hospital, Boston, MA, United States, 2Department of Growth and Development, Harvard School of Dental Medicine, Boston, MA, United States.

2:00 PM ­ 2:15 PM

Change in Paternity As a Risk Factor for Gastroschisis.
C.D. Chambers1, B.H. Chen1, K.A. Kalla2, K.L. Jones1. 1University of California, San Diego, La Jolla, CA, United States, 2Kaiser Permanente Medical Center, San Diego, CA, United States.

2:15 PM ­ 2:30 PM

Assisted Reproductive Techniques and the Risk of Oral Clefts: Data from the National Birth Defects Prevention Study, 1997­2000.
J. Reefhuis1, M. Honein1, S. Rasmussen1, A. Correa1, C. Hobbs2, A. Scheuerle3, L. Schieve4. 1National Center on Birth Defects and Developmental Disabilities, CDC, Atlanta, GA, United States, 2University of Arkansas for Medical Sciences, Little Rock, AR, United States, 3Texas Department of Health, Austin, TX, United States, 4National Center for Chronic Disease Prevention and Health Promotion, CDC, Atlanta, GA, United States.

2:30 PM ­ 2:45 PM

Maternal Obesity and Cardiovascular Malformations.
A. Correa-Villaseńor, C.J. Alverson. CDC, NCBDDD, Atlanta, GA, United States.

2:45 PM ­ 3:00 PM

Maternal Diabetes and Cardiovascular Malformations.
M.K. Thong2, A. Correa-Villaseńor1, C.J. Alverson1. 1CDC, NCBDDD, Atlanta, GA, United States, 2University of Malay, Department of Pediatrics, Kuala Lumpur, Malaysia.

3:00 PM ­ 3:15 PM

Break

3:15 PM ­ 3:30 PM

Diabetes, Body Mass Index, Vitamin Supplementation, and Anotia/Microtia.
M.M. Werler, J.E. Sheehan, A.A. Mitchell. Slone Epidemiology Center at Boston University, Boston, MA, United States.

3:30 PM ­ 3:45 PM

Impact of Maternal Alcohol Consumption on Sonographically­Visualized Fetal Brain Anatomy.
N.S. Handmaker2, W.F. Rayburn1, C. Meng2, B.B. Rayburn1, A. Wodajo2, V. Rappaport1. 1University of New Mexico, Obstetrics & Gynecology, Albuquerque, NM, United States, 2University of New Mexico, Psychology, Albuquerque, NM, United States.

3:45 PM ­ 4:00 PM

Placental Abnormalities Associated with Misoprostol Administration.
K.K. Vaux1, C.H. Chambers1, R. Chamit2, K. Benirschke3, E. Vanazzi4, K.L. Jones1. 1University of California, Department of Pediatrics, San Diego, CA, United States, 2University of California, San Diego, Department of Reproductive Medicine, San Diego, CA, United States, 3University of California, San Diego, Department of Pathology, San Diego, CA, United States, 4Universitat San Pablo, San Pablo, Brazil.

4:00 PM ­ 4:15 PM

Alcohol Dehydrogenase 3 Genotype and Risk for Oro-facial Clefts: Role of the Maternal and Fetal Genotypes.
C. Chevrier1, C. Perret2, A. Nelva3, C. Herman4, E. Robert-Gnansia5, M. Bahuau6, C. Francannet6, S. Cordier6. 1INSERM U435, Rennes, France, 2INSERM U 525, Faculté de médecine Pitié-Salpétričre, Paris, France, 3IEG, Lyon, France, 4CEMC Auvergne, Clermont-Ferrand, France, 5Service de Chirurgie Maxillo-faciale, Hôpital Trousseau, Paris, France, 6Service de Pédiatrie B, Hôtel-Dieu, Clermont-Ferrand, France.

4:15 PM ­ 4:30 PM

Evaluation of the Teratogenicity of Homocysteine in Rat Embryos Cultured In Vitro.
L.B. Fawcett, J.E. Pugarelli, R.L. Brent. Alfred I. duPont Hospital for Children, Department of Biomedical Science, Wilmington, DE, United States.

4:30 PM ­ 4:45 PM

Neurdevelopmental Outcome of Infants and Toddlers Exposed Prenatally to Selective Serotonin Reuptake Inhibitors.
S.N. Mattson1, K.E. Calarco1, K.K. Kao2, K.L. Jones2, C.D. Chambers2. 1Center for Behavioral Teratology, Deparment of Psychology, San Diego State University, San Diego, CA, United States, 2California Teratogen Information Service and Clinical Research Program, Department of Pediatrics, University of California, San Diego, San Diego, CA, United States.

4:45 PM ­ 5:00 PM

Prenatal Exposure to Fluconazole: An Identifiable Dysmorphic Phenotype.
E. Lopez-Rangel, M.I. Van Allen. University of British Columbia, Vancouver, Canada.
PLATFORM SESSION III
Genomics/Molecular Biology

1:00 PM ­ 1:15 PM

Temporal and Spatial Distribution of Steroidogenic Acute Regulatory Protein in Developing Male Sprague-Dawley Rats Following Transplacental Exposure to 17-?-Ethynyl Estradiol or Bisphenol A.
K.A. Hess, J.M. Naciff, G.J. Overmann, B.D. Richardson, L.M. Foertsch, G.P. Daston. Procter and Gamble Company, Miami Valley Laboratories, Central Product Safety, Cincinnati, OH, United States.

1:15 PM ­ 1:30 PM

Transplacental Exposure to 17alpha-Ethynyl Estradiol or Bisphenol A Induces a Specific Gene Expression Profile in the Developing Male Rat Reproductive System.
J. Naciff, K. Hess, B. Richardson, G. Overmann, L. Foertsch, S. Torontali, G. Carr, J. Tiesman, G. Daston. The Procter & Gamble Company, Miami Valley Laboratories, Cincinnati, OH, United States.

1:30 PM ­ 1:45 PM

Identification of Molecular Targets, Mechanisms and Biomarkers of Valproic Acid Teratogenicity Using a Toxicogenomics Approach.
M. Stigson, K. Kultima, A.M. Nyström, M. Jergil, B. Scholz, A.L. Gustafson, L. Dencker. Uppsala University, Department of Pharmaceutical Biosciences, Uppsala, Sweden.

1:45 PM ­ 2:00 PM

The Role of Antioxidant Enzymes and Transcription Factor NF-kB in Diabetic Embryopathy in the Cohen Diabetic Rat Model.
S.H. Ryu, S. Zangen, A. Ornoy. Hebrew University Hadassah Medical School, Jerusalem, Israel.

2:00 PM ­ 2:15 PM

Heat Shock Protein 70 (Hsp70) Protects Embryos From Hyperthermia-Induced Exencephaly: Analysis Using Hsp70 Null Mice.
M. Barrier1, S. Gil1, W.K. Kim2, P.E. Mirkes1. 1University of Washington, Department of Pediatrics, Seattle, WA, United States, 2Hanyan University, Department of Anatomy and Cell Biology, Seoul, Korea, South.

2:15 PM ­ 2:30 PM

Effects of Prenatal Exposure to Perfluorooctane Sulfonate on the Developing Lung in the Rat.
R.C. Grasty2, N. Roberts1, C.S. Lau1, B.E. Grey1, J.M. Rogers1. 1Reproductive Toxicology Division, NHEERL, Office of Research and Development, U.S. EPA, Research Triangle Park, NC, United States, 2Curriculum in Toxicology, University of North Carolina, Chapel Hill, NC, United States.

2:30 PM ­ 2:45 PM

Developmental Toxicity of the Antimalarial Artesunate in Rats and Rabbits.
T. White1, S. Clode2, I. Gaunt5, S. Ward3, C. Powell4, R. Clark1. 1GlaxoSmithKline, Safety Assessment Department, King of Prussia, PA, United States, 2Covance, Harrogate, North Yorkshire, United Kingdom, 3Liverpool School of Tropical Medicine, Liverpool, United Kingdom, 4GlaxoSmithKline, Safety Assessment Department, Ware, Hertfordshire, United Kingdom, 5Independent Consultant, London, United Kingdom.

2:45 PM ­ 3:00 PM

Maternal Folate Deficiency Exacerbates the Developmental Toxicity of 5-Fluorouracil in Rats.
B.D. Barbee, J.E. Andrews, B.E. Grey, H.P. Nicols, J.R. Thibodeaux, C.S. Lau, J.M. Rogers. U.S. EPA, Reproductive Toxicology Division, Research Triangle Park, NC, United States.

3:00 PM ­ 3:15 PM

Break

3:15 PM ­ 3:30 PM

Microarray Approaches to Identify Retinoid-Dependent Genes in Embryogenesis: Increased Collagen Fibril Production in a Model of Retinoid Insufficiency.
G.R. Flentke1, M.W. Baker1, K.E. Docterman1, S. Power1, J. Lough2, S.M. Smith1. 1Department of Nutritional Sciences, University of Wisconsin-Madison, Madison WI, United States, 2Department of Cell Biology, Anatomy & Neurobiology, Medical College of Wisconsin, Milwaukee, WI, United States.

3:30 PM ­ 3:45 PM

Reduced Birth Defects Caused by Maternal Immune Stimulation in Methylnitrosourea.
R. Prater1, E.D. Strahl2, K.L. Zimmerman2, D.L. Ward2, R.B. Gogal1, S.D. Holladay2. 1Edward Via Virginia College of Osteopathic Medicine, Department of Biomedical Sciences, Blacksburg, VA, United States, 2VMRCVM, Virginia Tech, Department of Biomedical Sciences and Pathobiology, Blacksburg, VA, United States.

3:45 PM ­ 4:00 PM

Integrating Human Genomics into Cluster Investigations of Birth Defects and Developmental Disabilities.
C.A. Moore1, M.L. Lindegren1, M.A. Honein2, S.A. Rasmussen2, S. Panse1, L. Nguyen1, P.W. Yoon1, M. Gwinn1, M.J. Khoury1. 1CDC, Office of Genomics and Disease Prevention, Atlanta, GA, United States, 2CDC, National Center on Birth Defects and Developmental Disabilities, Atlanta, GA, United States.

4:00 PM ­ 4:15 PM

Influence of an Engineered p53 Mutant Protein (m53DD) on Mitochondrial Functional State Studied with a Novel Chip-Based Cell Fluorescence Assay.
N.H. Owens, T.B. Knudsen. University of Louisville, School of Dentistry, Birth Defects Center, Louisville, KY, United States.

4:15 PM ­ 4:30 PM

Discovering System-Level Features of the Early Mouse Embryo during Alcohol Intoxication.
T.B. Knudsen, K.R. Nemeth, A.V. Singh. University of Louisville, School of Dentistry, Birth Defects Center, Louisville, KY, United States.

4:30 PM ­ 4:45 PM

A Digenic Cause of Cleft Lip in A-strain Mice and Definition of Candidate Genes for the Two Loci.
D.M. Juriloff, M.J. Harris, S.L. Dewell. Department of Medical Genetics, University of British Columbia, Vancouver, B.C., Canada.

4:45 PM ­ 5:00 PM

Reproductive and Developmental Toxicity of LY900003 (AFFINITAK), an Antisense Oligonucleotide to the mRNA of Human PKC-alpha, in the Mouse and Rabbit.
K.G. Hilbish1, A.E. Wakefield1, K.I. Griffey1, J.L. Hanes1, A.M. Vick1, V.R. Reddy1, S.P. Henry2, A.B. Astroff1. 1Lilly Research Laboratories, Eli Lilly & Company, Greenfield, IN, United States, 2ISIS Pharmaceuticals, Carlsbad, CA, United States.

5:00 PM - 6:00 PM BUSINESS MEETING
7:00 PM - 8:00 PM BANQUET RECEPTION
8:00 PM
WILSON AND FRASER BANQUET
F. Clarke Fraser Award Recipient: Karen Augustine, Bristol-Myers Squibb

 

Thursday, July 1

top

7:30 AM - 8:00 AM REGISTRATION AND CONTINENTAL BREAKFAST
7:30 AM - 11:30 AM WILEY-LISS SYMPOSIUM

The Role of Neural Crest Cells
Organized by Richard Miller, University of Rochester Medical Center; and Rocky Tuan, NIH/NIAMS
Sponsored by John Wiley and Sons

8:00 AM ­ 8:40 AM

The Biology of Neural Crest Cells
Speaker: Martin Garcia-Castro, California Institute of Technology

8:40 AM ­ 9:20 AM

The Role of Neural Crest Cells and Craniofacial Development
Speaker: Rob Krumlauf, Stowers Institute for Medical Research

9:20 AM ­ 9:40 AM

Break

9:40 AM ­ 10:20 AM

Cardiac Development and Cell Migration
Speaker: Cecilia Lo, National Heart Lung Blood Institute

10:20 AM ­ 11:00 AM

Neural Crest Cells in Cardiac Development
Speaker: Margaret Kirby, Duke University

12:00 PM ­ 4:00 PM

Council II Meeting

 

 



EXHIBITORS (as of March 15, 2004)

top

The Teratology Society thanks the following organizations for their participation as exhibitors at the 2004 Annual Meeting.

Biological Test Center Inc. National Library of Medicine
Hamilton Kinder, LLC

San Diego Instruments, Inc.

Huntingdon Life Sciences SkeleTech, Inc.
Instem LSS SNBL, Ltd.
ISIS BioComp Wiley, Inc.
   
   
   

 


2004 Sustaining Members (as of March 31, 2004)

top

The Teratology Society thanks the following Sustaining Members
for their support of the 2004 meeting


Platinum
Argus Research Laboratories, Inc.
Pfizer Global Research & Development

Gold
Aventis
ClinTrials BioResearch, Ltd. (CTBR)
GlaxoSmithKline
Hoffmann-La Roche, Inc.
Merck Research Laboratories

Silver
Abbott Laboratories
AstraZeneca
Bristol-Myers Squibb
ChevronTexaco
DuPont Haskell Laboratory
Eastman Kodak Company
Eli Lilly and Company
Mitretek Systems
Novartis Pharmaceuticals Corporation
Sanofi-Synthelabo Research
Schering-Plough Research


2004 Meeting Sponsors (as of March 31, 2004)

top

 

The Teratology Society thanks the following Sponsors
for their support of the 2004 meeting


Bristol-Myers Squibb
Centers for Disease Control
ChevronTexaco
ClinTrials BioResearch, Ltd. (CTBR)
DuPont Haskell Laboratory
Endo Pharmaceuticals, Inc.
John Wiley and Sons
March of Dimes
Middle Atlantic Reproduction
and Teratology Association
Midwest Teratology Association
MPI Research
National Institute of
Environmental Health Services
RTI International
U.S. Environmental Protection Agency

 

 

Updated 7-Jun-2004

© Copyright Teratology Society 1998-2002, 2003.
Please read our disclaimer.