TS 2010 Annual Meeting

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Meeting Program

(information subject to change)

Monday, June 28, 2010

7:00 AM–8:00 AM	2011 Program Committee Meeting—Skybox Meeting Room

7:00 AM–8:00 AM	BDRB Editorial Board Meeting—Filly Meeting Room

7:30 AM–6:00 PM	Registration—Marriott Ballroom VI Foyer

8:00 AM–7:00 PM	Exhibit Hall Open—Marriott Ballroom I

8:00 AM–9:00 AM	TS/OTIS Joint State-of-the-Art Lecture—Marriott Ballroom VI
	Palate Development: Molecular Perspectives and Current Understanding
	Robert M. Greene, University of Louisville

9:00 AM–9:15 AM	Break—Marriott Ballroom I

9:15 AM–11:45 AM	TS/OTIS/NBTS Joint Symposium—Marriott Ballroom VI
	Reproductive Psychiatry
	Chairpersons: Katherine L. Wisner, University of Pittsburgh Medical Center and Adrienne Einarson, The Motherisk Program

9:15 AM–9:20 AM	Introduction

9:20 AM–9:50 AM	Prenatal SRI Exposure: Where Does Neonatal Behavioral Syndrome End and Neurobehavioral Teratogenicity Begin?
	Tim F. Oberlander, University of British Columbia

9:50 AM–10:20 AM	Messages from the Womb: Maternal Antidepressant Use and Fetal Neurobehavior
	Amy L. Salisbury, Alpert Medical School of Brown University

10:20 AM–10:50 AM	An Update on Lithium Treatment during Pregnancy and Lactation
	Adele C. Viguera, Neurological Institute, Cleveland Clinic

10:50 AM–11:20 AM	Effects of Developmental Exposure to Methylphenidate on Brain Areas Involved in Cognition, Motivated Behaviors, Appetite and Stress
	Teresa Ann Milner, Weill Cornell Medical College

11:20 AM–11:45 AM	Discussion: How Do We Incorporate These Data into Human Risk Assessment?
	Katherine L. Wisner, University of Pittsburgh Medical Center

9:15 AM-11:45 PM	Platform Session II—Marriott Ballroom VII Mechanisms and Models
9:15 AM–9:30 AM	Peroxisome Proliferator-Activated Receptor Alpha (PPARγ), Beta (PPARβ), and Gamma (PPARβ) Expression in Human Fetal Tissues
	Abbott BD, Wood CR, Watkins AM, Das KP, Lau CS. Developmental Biology Branch, Toxicity Assessment Div., NHEERL, U.S. EPA, Research Triangle Park, NC, United States.

9:30 AM–9:45 AM	Modulation of Adenosine Receptor A₁ Signaling Results in Inhibition of Calvarial Ossification in Mice
	Bushdid PB, Gibbard A, Pagana JM, White TE. GlaxoSmithKline, King of Prussia, PA, United States.

9:45 AM–10:00 AM	Akt1 Mediates Mammary Gland Growth and Development In Vivo
	LaRocca J, Hixon M. Brown University, Providence, RI, United States.

10:00 AM–10:15 AM	Role of Mitogen-Activating Protein Kinase Signaling in the Developmental Toxicity of Hydroxyurea
	Banh S, Hales BF. McGill University, Montreal, QC, Canada.

10:15 AM–10:30 AM	Ethanol Teratogenesis, Oxidative Stress and Protection by a Free Radical Spin Trapping Agent
	Miller L¹, Wells PG². ¹Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada, ²Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada.

10:30 AM–10:45 AM	Advantages and Challenges of Dietary Developmental Toxicity Studies in the Rabbit
	Rasoulpour RJ, Brooks KJ, Saghir SA, Billington R, Carney EW. The Dow Chemical Company, Midland, MI, United States.

10:45 AM–11:00 AM	Cigarette Smoke Exposure: Alterations in the Metabolome of the Gravid and Non-Gravid Mouse Uterus
	Neal RE^1,2, Chen J¹, Birtles T², Greene RM², Pisano MM². ¹EOHS, SPHIS, University of Louisville, Louisville, KY, United States, ²Birth Defects Center, University of Louisville, Louisville, KY, United States.

11:00 AM–11:15 AM	Altered Liver Proteome Profiles in a Mouse Model of “Developmental” Cigarette Smoke Exposure
	Canales L¹, Chen J¹, Birtles T², Greene RM ², Pisano MM², Neal R^1,2. ¹University of Louisville, Louisville, KY, United States, ²Birth Defects Research Center, University of Louisville, Louisville, KY, United States.

11:15 AM–11:30 AM	Proteome Profiling of Mouse Embryonic Stem Cells to Define Markers for Cell Differentiation and Embryotoxicity
	Osman A^1,2, van Dartel DAM^1,2, Zwart E¹, Blokland M¹, Pennings J¹, Piersma AH^1,3. ¹RIVM Lab for Health Protection Research, Bilthoven, Netherlands, ²GRAT-NUTRIM-Maastricht University, Maastricht, Netherlands, ³IRAS-Utrecht University, Utrecht, Netherlands.

11:30 AM–11:45 AM	Development of a Computational (In Silico) Model of Ocular Teratogenesis
	Sipes NS¹, Rountree MR¹, Kleinstreuer NC¹, Dix DJ¹, Judson RS¹, Kavlock RJ¹, Swat M⁴, Glazier JA⁴, DeWoskin RS², Singh AV³, Spencer RM³, Knudsen¹. ¹NCCT, ORD, U.S. EPA, Research Triangle Park, NC, United States, ²NCEA, ORD, U.S. EPA, Research Triangle Park, NC, United States, ³Lockheed Martin, Research Triangle Park, NC, United States, ⁴The Biocomplexity Institute, Dept. of Physics, Indiana University, Bloomington, IN, United States.

11:45 AM–1:15 PM	Past Presidents’ Luncheon (By Invitation Only)—Bluegrass 1 Meeting Room

11:45 AM–1:15 PM	Lunch on Your Own

11:45 AM–12:45 PM	Web Site Committee Meeting —Filly Meeting Room

1:15 PM–2:15 PM	Special Lecture—Marriott Ballroom VI Human Teratogens: Update 2010
	Lewis B. Holmes, MassGeneral Hospital for Children

2:15 PM–5:00 PM	Update on Thalidomide Symposium—Marriott Ballroom VI
	Chairperson: Lewis B. Holmes, MassGeneral Hospital for Children

2:15 PM–2:20 PM	Introduction
	Lewis B. Holmes, MassGeneral Hospital for Children

2:20 PM–2:30 PM	Thalidomide Epidemic and the Founding of the Teratology Society
	F. Clarke Fraser, McGill University

2:30 PM–3:15 PM	Thalidomide Embryopathy: Ophthalmologic Findings and a Few Surprises
	Marilyn Miller, University of Illinois College of Medicine

3:15 PM–3:30 PM	Break

3:30 PM–4:15 PM	Recent Advances in Understanding the Developmental Basis of Phocomelia
	Patrick Allard, Harvard Medical School

4:15 PM–5:00 PM	Lessons Learned from the Thalidomide Epidemic and the Current Hypotheses of the Possible Mechanisms of Action
	Trent Stephens, Idaho State University



5:00 PM–7:00 PM	TS/NBTS/OTIS Joint Poster Session and Exhibits Open—Marriott Ballroom I
	Monday Poster Session Listings

7:30 PM–9:30 PM	MARTA Student and Postdoctoral Fellow Career Event—Bluegrass 1 Meeting Room Open to TS/NBTS/OTIS Students and Postdoctoral Fellows