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Agenda

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October 25–28, 2010
Sponsored by The Teratology Society

Course Director: Kok Wah Hew, Ph.D., DABT, Takeda Global R&D Center
Location: Noblis, Inc., 3150 Fairview Park Dr. South, Falls Church, VA 22042

This course is designed to provide a basic training in reproductive and developmental toxicology. Participants will obtain an overall understanding in reproductive and developmental biology, the principles of various testing approaches for reproductive and developmental toxicology, with strong emphasis on the practical application of these principles and interpretation of nonclinical safety data.

Who will benefit from this course?

  1. Scientists who have little or no training in this field and are interested in
    • starting a career in reproductive and developmental toxicology in the industry
    • managing reproductive and developmental toxicity studies as part of safety assessment, or
    • reviewing and interpreting reproductive and developmental toxicity data
  2. Experienced reproductive and developmental toxicologists who want to attend a refresher course

For those in category (1) above, the course will provide a broad basic and useful knowledge to help design and/or interpret reproductive and developmental toxicity studies.

For those in category (2) above, the course will provide a useful review of the basic biology of development and present an overview of the molecular biology of development.

For more information on this course please contact the Teratology Society.
Phone: (703) 438-3104 • E-mail: Teratology Society Headquarters

Course Overview

October 25

Male Reproductive Biology and Physiology
Paul Foster, National Toxicology Program, NIEHS

Female Reproductive Biology and Physiology
Paul Foster, National Toxicology Program, NIEHS

Embryology: From Fertilization to Neural Tube/Somite Formation
Sid Hunter, U.S. Environmental Protection Agency

Placenta and Maternal Influence on Development
Rich Miller, University of Rochester

Molecular Biology of Development
Rocky Tuan, University of Pittsburgh

Principles of Abnormal Development
John Rogers, U.S. Environmental Protection Agency

October 26

Normal and Abnormal Development of the Nervous System
Charles V. Vorhees, Cincinnati Children’s Hospital Medical Center

Normal and Abnormal Development of the Cardiovascular System
John DeSesso, Exponent

Normal and Abnormal Development of Head and Neck
Lori E. Kotch, U.S. Food and Drug Administration

Normal and Abnormal Development of the Respiratory and Digestive Systems
John DeSesso, Exponent

Normal and Abnormal Development of the Urogenital System
Kok Wah Hew, Takeda Global R&D Center

Normal and Abnormal Development of the Musculoskeletal System and Limbs
John Rogers, U.S. Environmental Protection Agency

October 27

PK/ADME of Xenobiotics during Pregnancy/Lactation and in Fetus/Newborn
Rick Corley, Pacific Northwest National Laboratory

Study Designs to Evaluate Reproductive Toxicity
Don Stump, WIL Research Laboratories, LLC

Study Designs to Evaluate Developmental Toxicity
Barry McIntyre, National Toxicology Program, NIEHS

Study Designs to Evaluate Pre- and Postnatal Toxicity
Don Stump, WIL Research Laboratories, LLC

Study Designs to Evaluate Toxicity in Juvenile Animals
Keith Robinson, Charles River

Regulatory Toxicology for Pharmaceuticals, Agricultural and Industrial Chemicals
Rochelle Tyl, RTI International

October 28

Interpretation of Data from Reproductive and Developmental Toxicity Studies
Rochelle Tyl, RTI International

Risk Assessment Using Reproductive and Developmental Toxicity Data
Gary Kimmel, Exponent



Rev. Thursday, June 17, 2010; at 12:53:08 AM EDT
The Society thanks our generous corporate Sponsors.
© Copyright Teratology Society 2009.
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