Program

Meeting Agenda

Teratology Society 2019 Annual Meeting—Sea Changes in Birth Defects Research and Prevention

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Only sessions designated with CME are eligible for Continuing Medical Education credit.

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3:00 PM–6:00 PM


7:30 AM–6:00 PM


8:00 AM–8:30 AM


8:30 AM–12:00 Noon

Organized by the Education Committee,
Chairperson: Amy L. Williams, Exponent, Inc.



8:30 AM–8:40 AM


8:40 AM–8:45 AM
8:45 AM–9:30 AM


9:30 AM–10:15 AM


10:15 AM–10:30 AM


10:30 AM–11:15 AM


11:15 AM–12:00 Noon


12:00 Noon–1:30 PM


2:00 PM–7:00 PM


1:30 PM–5:00 PM

Organized by the Education Committee
Chairperson: Amy L. Williams, Exponent, Inc.



1:30 PM–1:35 PM


1:35 PM–2:13 PM


2:13 PM–2:51 PM


2:51 PM–3:29 PM


3:29 PM–3:44 PM


3:44 PM–4:22 PM


4:22 PM–5:00 PM

4:45 PM–5:00 PM



5:00 PM–7:00 PM


7:00 AM–6:00 PM


7:00 AM–4:00 PM


7:00 AM–8:00 AM


7:30 AM–8:00 AM


8:00 AM–8:15 AM


8:15 AM–9:00 AM


9:05 AM–12:05 PM





9:05 AM–9:10 AM


9:10 AM–9:30 AM
1


9:30 AM–9:50 AM
2


9:50 AM–10:10 AM
3


10:10 AM–10:30 AM
4


10:30 AM–10:45 AM
5


10:45 AM–11:05 AM


11:05 AM–11:25 AM
6


11:25 AM–11:45 PM
7


11:45 PM–12:05 PM
8


12:05 PM–1:30 PM


12:05 PM–1:30 PM


12:30 PM–1:30 PM


12:30 PM–1:30 PM


1:30 PM–2:00 PM


2:00 PM–2:30 PM


2:35 PM–5:30 PM



2:35 PM–3:10 PM
S1
3:10 PM–3:45 PM
S2


3:45 PM–4:00 PM


4:00 PM–4:35 PM
S3


4:35 PM–5:10 PM
S4


5:10 PM–5:30 PM


2:35 PM–5:30 PM


2:35 PM–3:10 PM
S5


3:10 PM–3:45 PM
S6


3:45 PM–4:00 PM


4:00 PM–4:35 PM
S7


4:35 PM–5:10 PM
S8


5:10 PM–5:30 PM


5:35 PM–6:00 PM


6:00 PM–8:00 PM


 

P1

Lachenauer ER1, Stabler SP2, Field MS1, Stover PJ3. 1Cornell University, Ithaca, NY, United States, 2University of Colorado, Aurora, CO, United States, 3Texas A&M University, College Station, TX, United States. p53 Disruption Increases Uracil Accumulation in DNA and Leads to Folic Acid Nonresponsive Neural Tube Defects in Mice

 

P2

Harrison DB, Wang L, Gaitan A, Stamen MN, Lane SR, Bultman JD, Coder PS. Charles River Laboratories, Ashland, OH, United States. The Use of Female Mice Implanted with Vascular Access Buttons (VABs) in Reproduction Studies

 

P3

Jia Y1,2,3, Jiang J1,2,3, Yang Y1,2,3, Chong L1,2,3, Mao X1,2,3, Zhou L1,2,3, Sun Z1,2,3. 1Shanghai Institute of Planned Parenthood Research, National Evaluation Center for Toxicology of Fertility Regulating Drugs, 2National Population and Family Planning Key Laboratory of Contraceptive Drugs and Devices, 3Reproductive and Developmental Research Institute, Fudan University, Shanghai, Shanghai, China. Background Data of SD Rats in Embryo-Fetal Development Toxicity Study

 

P4

Dodd-Butera T1,2, Beaman M2, Li H3. 1Azusa Pacific University, San Diego, CA, United States, 2CSU San Bernardino, San Bernardino, CA, United States, 3Azusa Pacific University, Azusa, CA, United States. Poisoning and Pregnancy: A Review from the National Poison Data System

 

P5

Chen H1, Williams KE1, Kapidzic M1, Kwan E1, Aburajab R1, Hunter CL2, Fisher SJ1, Robinson JF1. 1University of CaliforniaSan Francisco, San Francisco, CA, United States, 2AB SCIEX, Redwood City, CA, United States. Brominated Flame Retardant BDE-47 Induces Proteomic Alterations in Primary Human Villous Cytotrophoblasts

 

P6

Derrick DJ1, Wolton K2, Currie R2, Tindall MJ1. 1Department of Mathematics and Statistics, University of Reading, Reading, Berkshire, United Kingdom, 2Syngenta, Jealott’s Hill International Research Centre, Bracknell, Berkshire, United Kingdom. A Mathematical Model of the Role of Aggregation in Sonic Hedgehog Signalling

 

P7

Cortés OD, López Serna N. Autonomous University of Nuevo Leon, Monterrey, Nuevo Leon, Mexico. Facial Dysmorphology As an Indicator of Organ Malformation: A Report of Two Cases

 

P8

Cheng V, Reddam A, Dasgupta S, Volz DC. University of CaliforniaRiverside, Riverside, CA, United States. PPARγ Agonist-Induced Disruption of Dorsoventral Patterning in Zebrafish

 

P9

Sheehy O1, Zhao J-P1, Berard A1,2. 1CHU Sainte-Justine Research Center, Montréal, QC, Canada, 2Faculty of Pharmacy, University of Montréal, Montréal, QC, Canada. Incident Exposure to Benzodiazepine in Early Pregnancy and the Risk of Spontaneous Abortion

 

P10

Berard A1,2,3, Abbas-Chorfa F4, Kassai B3,5,6, Vial T3,5,7, Nguyen K3,5,6, Sheehy O1, Schott A8,9. 1Research Center, CHU Sainte-Justine, Montréal, QC, Canada, 2Faculty of Pharmacy, University of Montréal, Montréal, QC, Canada, 3EPICIME-CIC 1407 Lyon, Inserm, Pharmacotoxicology Department, CHU-Lyon, Bron, France, 4Hospices Civils de Lyon, Service de biostatistique-bioinformatique, Pôle Santé Publique, Lyon, France, 5University of Lyon 1, Lyon, France, 6Laboratoire de Biométrie et Biologie Evolutive, University of Lyon 1, CNRS, Villeurbanne, France, 7Service Hospitalo-Universitaire de Pharmacotoxicologie, CHU-Lyon, Lyon, France, 8Hospices Civils de Lyon, Pôle de Santé Publique, Lyon, France, 9Université Lyon Claude Bernard Lyon 1, Lyon, France. The French Pregnancy Cohort: Prevalence and Trend of Medication Use during Pregnancy in the French Population

 

P11

Knudsen TB1, Zurlinden TJ2, Saili KS2, Baker NC3. 1US EPA/ORD/NCCT, Research Triangle Park, NC, United States, 2USEPA/ORD/NCCT, Research Triangle Park, NC, United States, 3Leidos, Research Triangle Park, NC, United States. ToxCast Embryonic Stem Cell (H9) Profiling for Predicting Developmental Toxicity

 

P12

Moris N1, Turner DA1, Schroeder J2, Baranowski A1, Anlas K3, Martinez Arias A1. 1Department of Genetics, University of Cambridge, Cambridge, Cambridgeshire, United Kingdom, 2University of Heidelberg, Heidelberg, Baden-Württemberg, Germany, 3EMBL, Barcelona, Barcelona, Spain. Gastruloids: An Embryonic Stem Cell-Based In Vitro Model of Human Development

 

P13

Racz PI, Brandsma I, Zwetsloot T, Hartvelt S, Hendriks G. Toxys BV. Leiden, South-Holland, The Netherlands. Validation of a Novel Human Stem Cell-Based Gene Expression Assay for In Vitro DART Assessment

 

P14

Silva MH1, Koshlukova S1, Rubin A1, Lohstroh P1, Kalashnikova A1, Kwok E1, DuTeaux S1, Verder-Carlos M2. 1Human Health Assessment Branch, Department of Pesticide Regulation, California EPA, Sacramento, CA, United States, 2Department of Pesticide Regulation, California EPA, Sacramento, CA, United States. Hazard Identification for the Herbicide Propyzamide

 

P15

Marsden E1, Vignand P1, Loheac E2, Briffaux J-P1. 1Charles River Laboratories France Safety Assessment SAS, Saint-Germain-Nuelles, Rhone-Alpes, France, 2Charles River Laboratories France, Saint-Germain-Nuelles, Rhone-Alpes, France. Method Development for Intrauterine Administration of a Contrast Agent in the Rat for a Safety Evaluation Including Developmental and Reproductive Toxicology Endpoints

 

P16

Lee J1,2, Yu W-J1, Choi S-J3, Jeong J-S1, Kim SY1, Shin Y-J1, Kim W4, Lee K3,5, Lee S-H3, Jeong EJ1, Nam S-Y2. 1Developmental and Reproductive Toxicology Research Group, Korea Institute of Toxicology, Youseong-gu, Daejeon, The Republic of Korea, 2College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungcheongbuk-do, The Republic of Korea, 3Inhalation Toxicology Research Group, Korea Institute of Toxicology, Jeongeup, Jeollabuk-do, The Republic of Korea, 4Toxicological Pathology Research Group, Korea Institute of Toxicology, Youseong-gu, Daejeon, The Republic of Korea, 5Department of Human and Environmental Toxicology, University of Science & Technology, Youseong-gu, Daejeon, The Republic of Korea. Polyhexamethylene Guanidine Phosphate Inhalation Exposure during the Pregnancy in Rats: Effects on Postnatal Development of Offspring and Maternal Functions

 

P17

Viens L1, Fleck-Derderian S2, Baez-Santiago M3, Oduyebo T4, Broussard C4, Meaney-Delman D4. 1Chickasaw Nation Industries, Inc., Norman, OK, United States, 2Oak Ridge Institute for Science and Education, Oak Ridge, TN, United States, 3Eagle Medical Services, San Antonio, TX, United States, 4Centers for Disease Control and Prevention, Atlanta, GA, United States. Congenital Zika Syndrome: A Systematic Review of the Role of Prenatal Ultrasound and Amniocentesis

 

P18

Nalbandyan M1, Howley MM1, Cunniff CM2, Romitti PA3, Browne ML1. 1Congenital Malformations Registry, New York State Department of Health, Albany, NY, United States, 2Division of Medical Genetics, Department of Pediatrics, New York-Presbyterian Hospital/Weill Cornell Medicine, New York, NY, United States, 3Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA, United States. Descriptive and Risk Factor Analysis of Sacral Agenesis: National Birth Defects Prevention Study, 1997–2011

 

P19

Cho SJ, Getschel M, Hort M, Peterson K. Minnesota Department of Health, St. Paul, MN, United States. Lessons from Craniosynostosis Ascertainment Using 2015–2017 Birth Cohorts in Minnesota

 

P20

Sowunmi S, Eckert V, Olney R. California Department of Public Health, Richmond, CA, United States. Assessing the Utility of Public Health Laboratory-Reported Clinical Data for Use in Extended Zika Birth Defects Surveillance in California

 

P21

Shumate CJ1, Hoyt AT1, Tarpey M1, Canfield MA1, Lopez KN2. 1Texas Department of State Health Services, Birth Defects Epidemiology and Surveillance Branch, Austin, TX, United States, 2Division of Pediatric Cardiology, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, United States. Survival of Texas Heterotaxy Cases from Birth to Ten-Years

 

P22

Hoyt AT1, Ramadhani T2, Shumate CJ1, Canfield MA1, Le M1, Scheuerle AE3. 1Birth Defects Epidemiology and Surveillance Branch, Texas Department of State Health Services, Austin, TX, United States, 2Health and Human Services, Austin, TX, United States, 3University of Texas Southwestern Medical Center, Dallas, TX, United States. Acculturation and Selected Birth Defects Among Non-Hispanic Blacks in a Population-Based Case-Control Study

 

P23

Ren A1,2, Pi X1,2, Jin L1,2, Li Z1,2, Wang L1,2. 1Institute of Reproductive and Child Health, Peking University, Beijing, China, 2Ministry of Health Key Laboratory of Reproductive Health, Peking University, Beijing, China. Trace Elements in Placental Tissue and Risk of Orofacial Clefts

 

P24

Brannen KC, Robinson BL, Mattson BA. Merck, West Point, PA, United States. Detecting Teratogenicity with Micro-CT Skeletal Evaluations in Nonclinical Studies

 

P25

Barbeau S, Adamo M, Pouliot L, Robinson K. Charles River, Montréal, QC, Canada. An Assessment of Continuous Intravenous and Subcutaneous Infusion Dosing in Embryo-Fetal Development Studies: Maternal and Embryo-Fetal Parameters

 

P26

Solomon HM, Murzyn S, Rendemonti JE, Chapman SP, Junker BM, Stanislaus DJ, Alsaid H. GlaxoSmithKline Pharmaceuticals, Collegeville, PA, United States. Application of micro-CT Imaging in a Preliminary Embryo-Fetal Development Study in New Zealand White Rabbits

 

P27

Schellpfeffer MA1, Strasburger JF2, Fihlo OB3, Bitant S4, Wakai RT4. 1Medical College of Wisconsin, Milwaukee, WI, United States, 2Children's Hospital of Wisconsin, Milwaukee, WI, United States, 3Universidade de San Paulo, San Paulo, Brazil, 4University of Wisconsin-Madison, Madison, WI, United States. Optically-Pumped Magnetocardiography to Noninvasively Obtain Electrocardiograms in the Developing Chick Embryo

 

P28

Emily M, McCuistion EA, Bailey M. Emporia State University, Emporia, KS, United States. Changes in Cyp2b10 and Gsta4 Gene Expression during Cyclophosphamide Exposure and Maternal Restraint Stress

 

P29

Conley JM, Lambright CS, Evans N, Medlock-Kakaley E, Wilson VS, Gray E. US EPA/ORD/NHEERL/TAD, Research Triangle Park, NC, United States. Adverse Effects of Gestational Exposure to Hexafluoropropylene Oxide Dimer Acid (GenX) in the Sprague-Dawley Rat

 

P30

Paradis F-H1, Beaudry F1, Tavcar R1, Kubaszky R1, Downey AM1, Ellemann-Laursen S2, Makin A2, Hill K3, Gilmore R3, Singh P4, Hargitai J5, Spezia F4, Forster R4, Authier S1. 1Citoxlab North America, Montréal, QC, Canada, 2Citoxlab Denmark, Ejby, Denmark, 3Citoxlab USA, LLC, Stilwell, KS, United States, 4Citoxlab France, Evreux, France, 5Citoxlab Hungary, Veszprem, Hungary. Interspecies Comparison of Embryo-Fetal Data among Control Groups of Sprague-Dawley Rats, New Zealand White Rabbits, and Gottingen Minipigs

 

P31

Williams AL1, Campetella S2, DeSesso JM1. 1Exponent, Inc., Alexandria, VA, United States, 2Galderma, S.A., Lausanne, Switzerland. Retinoid Teratogenicity: A Critical Evaluation of Contributing Properties for Adapalene

 

P32

Buckley DM, Sidik A, Kar RD, Eberhart JK. The University of Texas at Austin, Austin, TX, United States. Differentially Sensitive Neurons in the Central Nervous System and Formation of Hindbrain Heterotopias in Ethanol-Exposed Zebrafish

 

P33

Ding Z, Yang S, Pan L, McPherson S. WuxiApptec, Suzhou, Wuzhong, China. Comparison of Historical Control Data for Fertility and Early Embryonic Development Toxicity Parameters in Sprague-Dawley Rats from Different Geographical Regions

 

P34

Katzman PJ. University of Rochester Medical Center, Rochester, NY, United States. Pulmonary Hypoplasia in a Lethal Case of Pallister-Hall Syndrome

 

P35

Hootnick DR1,2,3. 1Department of Orthopedic Surgery, SUNY Upstate Medical University, Syracuse, NY, United States, 2Department of Pediatrics, SUNY Upstate Medical University, Syracuse, NY, United States, 3Department of Cellular and Molecular Biology, SUNY Upstate Medical University, Syracuse, NY, United States. Does Embryonic Arterial Maldevelopment Present a Risk Factor for Congenital Long Bone Deficiencies?

 

P36

Hamm J1, Behl M2, Ceger P1, Haendel M3, Marvel S4, Maull EA2, Muriana A5, Reif D4, Tanguay RL6, Thessen A3, Truong L6, Vallant M2, Walker N2, Ryan K2. 1ILS, Research Triangle Park, NC, United States, 2NIH/NIEHS/DNTP, Research Triangle Park, NC, United States, 3Oregon State University, Corvallis, OR, United States, 4North Carolina State University, Raleigh, NC, United States, 5Biobide USA, Cambridge, MA, United States, 6Sinnhuber Aquatic Research Laboratory, Oregon State University, Corvallis, OR, United States. The National Toxicology Program’s Systematic Evaluation of the Application of Zebrafish in Toxicology: SEAZIT

 

LB1

Zamek-Gliszczynski MJ1, Zhang X2, Mudunuru J1, Du Y2, Chen JL2, Taskar KS3, Huang J2, Huang Y2, Romach EH4. 1GlaxoSmithKline, Collegeville, PA, United States, 2BioIVT, Santa Clara, CA, United States, 3GlaxoSmithKline, Ware, United Kingdom, 4ViiV Healthcare, Research Triangle Park, NC, United States. Effects of Dolutegravir and Other Integrase Inhibitors on Folate Transport Pathways

 

LB2

Kancherla V1,2, Averbach H3, Oakley Jr GP1,2. 1Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA, United States, 2Center for Spina Bifida Prevention, Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA, United States, 3Department of Environmental Health, Emory University Rollins School of Public Health, Atlanta, GA, United States. Nation-Wide Failure of Voluntary Folic Acid Fortification of Corn Masa Flour and Tortillas with Folic Acid

 

LB3

Klos, KS; Goeden, HM; Fallace, KL. Minnesota Department of Health, St. Paul, MN, United States. Combined Boron Content in Infant Formula and Drinking Water Raises Developmental Concerns

 

LB4

Wolf CJ1, Becker C2. 1Toxicity Assessment Division, National Health and Environmental Effects Research Lab, US EPA, Research Triangle Park, NC, United States, 2Oak Ridge Institute for Research Education, Oak Ridge, TN. United States. Multicellular Organoid Model of Human Palatal Fusion and Response to Valproic Acid

 

LB5

Hannas BR1, Coder PS2, Harrison D2, Mikles K1, Papineni S3, Murphy L3, Domoradzki J3, Rasoulpour RJ3, Terry C3. 1Corteva Agriscience, Corteva Global Laboratory, Newark, DE, Untied States, 2Charles River Laboratories, Ashland, OH, United States, 3Corteva Agriscience, Indianapolis Headquarters, Indianapolis, IN, United States. Dietary Route of Exposure for Rabbit Provides a Reliable, Relevant, and Conservative Characterization of Developmental Toxicity

 

 


8:00 PM–8:30 PM


7:00 AM–6:00 PM


7:00 AM–4:00 PM


7:00 AM–8:00 AM


7:00 AM–8:00 AM


7:00 AM–8:00 AM


7:00 AM–8:00 AM


7:30 AM–8:00 AM


8:00 AM–9:00 AM


9:05 AM–12:00 Noon

Chairpersons: Carl L. Keen, University of California–Davis and
Helen J. K. Sable, University of Memphis



9:05 AM–9:15 AM


9:15 AM–9:45 AM
S9


9:45 AM–10:15 AM
S10


10:15 AM–10:30 AM


10:30 AM–11:00 AM
S11


11:00 AM–11:30 AM
S12


11:30 AM–12:00 Noon
S13


9:05 AM–12:00 Noon
CME



9:05 AM–9:25 AM
S14


9:25 AM–9:55 AM
S15


9:55 AM–10:25 AM
S16


10:25 AM–10:40 AM


10:40 AM–11:10 AM
S17


11:10 AM–11:40 AM
S18


11:40 AM–12:00 Noon


12:00 Noon–2:00 PM


12:00 Noon–1:30 PM


12:00 Noon–2:00 PM



12:00 Noon–12:10 PM


12:10 PM–12:40 PM
W1


12:40 PM–1:10 PM
W2


1:10 PM–1:40 PM
W3


1:40 PM–2:00 PM
W4


2:00 PM–2:30 PM


2:35 PM–5:50 PM
CME


2:35 PM–2:40 PM


2:40 PM–3:20 PM
S19


3:20 PM–4:00 PM
S20


4:00 PM–4:15 PM


4:15 PM–4:55 PM
S21


4:55 PM–5:35 PM
S22


5:35 PM–5:50 PM


2:35 PM–5:50 PM

Chairpersons: Christina D. Chambers, University of California–San Diego and
Marcy Stephens Powell, GlaxoSmithKline



2:35 PM–2:40 PM


2:40 PM–3:20 PM
S23


3:20 PM–4:00 PM
S24


4:00 PM–4:15 PM


4:15 PM–4:55 PM
S25


4:55 PM–5:35 PM
S26


5:35 PM–5:50 PM


6:00 PM–8:00 PM


 

P37

Schneuer FJ1, Milne E2, Jamieson SE2, Pereira G3, Hansen M2, Barker A4, Holland AJ5, Bower C2, Nassar N1. 1The Children's Hospital at Westmead Clinical School, The University of Sydney, Sydney, NSW, Australia, 2Telethon Kids Institute, University of Western Australia, Perth, WA, Australia, 3School of Public Health, Curtin University, Perth, WA, Australia, 4Department of Paediatric Surgery, Princess Margaret Hospital for Children, Perth, WA, Australia, 5The Children’s Hospital at Westmead Clinical School, The University of Sydney, Sydney, NSW, Australia. The Link between Male Genital Anomalies and Adult Male Reproductive Disorders: A Population-Based Data Linkage Study Spanning over 40 Years

 

P38

Hrubec TC1,2, Vieira P1, McDonald VA1. 1Edward Via College of Osteopathic Medicine Virginia Campus, Blacksburg, VA, United States, 2VA-MD College of Veterinary Medicine, Virginia Tech, Blacksburg, VA, United States. Hormones Anyone? How QACs Reduce Reproductive Capability

 

P39

Howdeshell KL1, Shelby MD1, Blain RB2, Lunn RM1, Ross P2, Taylor KW1, Witt KL1, Rooney AA1. 1NIEHS/NTP, Research Triangle Park, NC, United States, 2ICF, Durham, NC, United States. NTP Monograph on the Systematic Review of Occupational Exposure to Cancer Chemotherapy Agents and Adverse Health Outcomes

 

P40

Schanzer A1, Kappil M2, Blum J1, Chen L-C1, Chen J2, Zelikoff J1. 1New York University, New York, NY, United States, 2Mount Sinai Icahn School of Medicine, New York, NY, United States. Differential Expression Analysis of Preterm Birth Genes in Placenta of PM2.5 Exposed Mice Using RNAseq

 

P41

Bowman CJ1, Bono CP1, Nowland WS1, Ji C2. 1Pfizer, Groton, CT, United States, 2Pfizer, La Jolla, CA, United States. Placental Transfer of the Immunoglobulin G Response to KLH in Rats and Rabbits

 

P42

Nestoridi E1, Flaherty K2, Liberman RF1, Higgins CA1, Yazdy MM1. 1Massachusetts Center for Birth Defects Research and Prevention, Massachusetts Department of Public Health, Boston, MA, United States, 2Katherine Flaherty Consulting, LLC, Franklin, MA, United States. Implementation and Impact of Incorporating Prenatal Diagnoses of Birth Defects into an Active State-Wide Surveillance System

 

P43

Howey XM1, Phelps D1, Weitekamp C1, Zurlinden TJ2, Catron T1, Keely S3, Brinkman N3, Wheaton E3, Tal T4. 1ORISE/US EPA/ORD/NHEERL/ISTD, Research Triangle Park, NC, United States, 2US EPA/ORD/NCCT, Research Triangle Park, NC, United States, 3US EPA/ORD/NERL/SED, Research Triangle Park, NC, United States, 4US EPA/ORD/NHEERL/ISTD, Research Triangle Park, NC, United States. Identifying Microbial Markers of Xenobiotic Exposures in Zebrafish

 

P44

Watanabe M1,2, Ford SM1,2, Liu Y3, Broberg MC4, Kim JW1, Herring AI1, Rollins AM3, Zhu A5, Kumar N5, Lapierre-Landry M3, Kolesova H1,2, Jenkins MW3. 1Case Western Reserve University School of Medicine, Cleveland, OH, United States, 2Department of Pediatrics, Rainbow Babies and Children's Hospital, Cleveland, OH, United States, 3Department of Biomedical Engineering, Case Western Reserve University, School of Engineering, Cleveland, OH, United States, 4Department of Pediatrics, Rainbow Babies and Children's Hospital, Cleveland, OH, United States, 5Hathaway Brown, Science Research & Engineering Program, Shaker Heights, OH, United States. Novel Methods for Imaging Congenital Heart Defects in an Avian Model of Fetal Alcohol Spectrum Disorder

 

P45

Zhao J-P1, Sheehy O1, Berard A1,2. 1CHU Sainte Justine, Montréal, QC, Canada, 2Faculty of Pharmacy, University of Montréal, Montréal, QC, Canada. Impact of Nonadjustment for Smoking Status during Pregnancy and Prepregnancy Obesity on the Association between Gestational Antidepressant Use and Risk of Low Birth Weight Infants

 

P46

Jo YS. Department of Obstetrics and Gynecology, College of Medicine, St. Vincent's Hospital, The Catholic University of Korea, Suwon, Kyeonggi, The Republic of Korea. Nonobstetric Surgery during Pregnancy and Perioperative Fetal Monitoring

 

P47

Palmer JA1, Glatt CM2, Colwell MR1, Donley EL1, Burrier RE1. 1Stemina Biomarker Discovery, Inc., Madison, WI, United States, 2The Chemours Company, Wilmington, DE, United States. Developmental Toxicity Testing of Gaseous Chemicals with a Human Pluripotent Stem Cell-Based Assay

 

P48

DeSesso JM1,2, Coder PS3, York RG4, Budinsky RA5, Pottenger LH6, Sen S7, Lucarell JM3, Bevan CJ8, Bus JS9. 1Exponent, Alexandria, VA, United States, 2Georgetown University School of Medicine, Washington, DC, United States, 3Charles River Laboratories, Ashland, OH, United States, 4RG York and Associates LLC, Cincinnati, OH, United States, 5Dow Chemical Company, Midland, MI, United States, 6LHP Tox Consult LLC, Midland, MI, United States, 7Chrlaes River Laboratories, Ashland, OH, United States, 8HSIA, Arlington, VA, United States, 9Exponent, Midland, MI, United States. Trichloroethylene (TCE) in Drinking Water Does Not Cause Heart Defects in Rats

 

P49

Baker AE1, Fuchs A2, Millen L1, Ervin T1, Luetjens M2, Weinbauer GF2. 1Covance Laboratories Inc., Madison, WI, United States, 2Covance Preclinical Services GmbH, Muenster, Westphalia, Germany. Intranasal Oxytocin Administration as a Procedure for Handling Infant Rejections in Long‑Tailed Macaques (Macaca fascicularis)

 

P50

Pitsava G1, Feldkamp ML2, Pankratz N3, Lane J3, Kay DM4, Shaw GM5, Reefhuis J6, Jenkins MM6, Almli LM6,7, Werler M8, Olshan AF9, Pangilinan F10, Brody LC10, Romitti PA11, Mills JL1, UW Center for Mendelian Genomics12, NISC Comparative Sequencing Program13, The National Birth Defects Prevention Study14. 1NICHD, NIH, Bethesda, MD, United States, 2University of Utah, Salt Lake City, UT, United States, 3University of Minnesota, Minneapolis, MN, United States, 4New York Department of Health, Albany, NY, United States, 5Stanford University, Stanford, CA, United States, 6NCBDDD, CDC, Atlanta, GA, United States, 7Carter Consulting Inc., Atlanta, GA, United States, 8Boston University, Boston, MA, United States, 9University of North Carolina, Chapel Hill, NC, United States, 10NHGRI, NIH, Bethesda, MD, United States, 11Univeristy of Iowa, Iowa City, IA, United States, 12University of Washington, Seattle, WA, United States, 13National Institutes of Health, Rockville, MD, United States, 14Centers for Disease Control and Prevention, Atlanta, GA United States. Exome Sequencing Identifies Genes Involved in Cell Adhesion and Migration in Bladder Exstrophy Cases

 

P51

Kancherla V1, Ma C2, Grant G3, Lee HC2, Hintz SR2, Carmichael SL2. 1Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, United States, 2Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA, United States, 3Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, United States. Factors Associated with First-Year Mortality in Infants with Myelomeningocele

 

P52

Santiago-Colón A1, Rocheleau C1, Chen I-C1, Sanderson W2, Waters M1, Lawson CC1, Langlois PH3, Cragan J4, Reefhuis J4. 1Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Cincinnati, OH, United States, 2University of Kentucky, Lexington, KY, United States, 3Texas Department of State Health Services, Birth Defects Epidemiology and Surveillance Branch, Austin, TX, United States, 4National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA, United States. Association between Maternal Occupational Exposure to Polycyclic Aromatic Hydrocarbons and Rare Birth Defects of the Face and Central Nervous System in the National Births Defects Prevention Study

 

P53

Gorgui J1,2, Sheehy O2, Trasler J3, Fraser W4, Berard A1,2. 1Faculty of Pharmacy, University of Montréal, Montréal, QC, Canada, 2Research Center-CHU Sainte-Justine, Montréal, QC, Canada, 3Department of Pediatrics, Human Genetics and Pharmacology & Therapeutics, McGill University, Montréal, QC, Canada, 4Faculty of Medicine and Health Sciences, University of Sherbrooke, Sherbrooke, QC, Canada. Medically Assisted Reproduction and the Risk of Being Born Small for Gestational Age

 

P54

Papadopoulos EA, Fisher S, Howley MM, Browne ML. New York State Department of Health, Albany, NY, United States. Maternal Hereditary Hemolytic Anemia and Birth Defects in the National Birth Defects Prevention Study

 

P55

Krause KH1,2, Ailes E1, Gilboa SM1, Tong V1, Cragan J1, Delaney A1, Jones A1, Nahabedian J1, Olson SM1,3, Roth N1, Smoots A1, Yowe-Conley T1, Meaney-Delman D1, Honein M1. 1Centers for Disease Control and Prevention, Atlanta, GA, United States, 2Epidemic Intelligence Service, Atlanta, GA, United States, 3G2S Corporation, San Antonio, TX, United States. An Evaluation of Zika Birth Defects Surveillance: A Model for Rapid Surveillance of Birth Defects during an Emergency Response—United States, 2018

P56

Michikawa T1,2, Yamazaki S2, Ono M2, Kuroda T3, Nakayama SF2, Suda E2, Isobe T2, Iwai-Shimada M2, Kobayashi Y2, Tamura K2, Yonemoto J2, Kawamoto T2, Nitta H2. 1Toho University, Tokyo, Japan 2National Institute for Environmental Studies, Tsukuba, Ibaraki, Japan 3Keio University School of Medicine, Tokyo, Japan. Fish Intake Was Inversely Associated with Congenital Gastrointestinal Tract Atresia: The Japan Environment and Children’s Study

 

P57

Lemelin M1,2, Boukhris T1,2, Sheehy O2, Berard A1,2. 1Faculty of Pharmacy, University of Montréal, Montréal, QC, Canada, 2CHU Sainte-Justine Research Center, Montréal, QC, Canada. Prevalence and Predictors of ADHD Medication Use in a Cohort of Pregnant Women

 

P58

McCall JL, Varney ME, Blethen KE, Elliott M, Damron FH, Barnett JB. West Virginia University, Morgantown, WV, United States. Prenatal Exposure to Cadmium Alters the Transcriptome of Regulatory T-cells in C57BL/6 Mice

 

P59

Harrison DB, Herberth MT, Edwards TL, Hackman ML, Coder PS. Charles River Laboratories, Ashland, OH, United States. Evaluation of Pregnancy Rates and Developmental Toxicity Endpoints in Time-Mated Mice

 

P60

Shankar P1, Geier M1, Truong L1, McClure R2, Pande P2, Waters KM2, Tanguay RL1. 1Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, United States, 2Pacific Northwest National Laboratory, Richland, WA, United States. Coupling Transcriptomics and Developmental Toxicity in Zebrafish to Classify Polycyclic Aromatic Hydrocarbons (PAHs)

 

P61

Adamo M, Jouniaux J, Barbeau S, Pouliot L, Robinson K. Charles River Montréal, Montréal, QC, Canada. A Microsampling Method for Juvenile Mouse Studies

 

P62

Cope H, Blake BE, Fenton SE. NTP Laboratory, Division of the NTP, NIEHS, Durham, NC, United States. Evaluation of Puberty and Metabolic Disease in CD-1 Mice Exposed to PFOA or GenX

 

P63

Murphy CJ1, Goodnight SY1, Babineau RZ1, Dorato MA1, Harris SB2. 1Smithers Avanza, Gaithersburg, MD, United States, 2Stephen B. Harris Group, San Diego, CA, United States. Evaluation of the Teratogenic Effects Produced When Dimethadione Was Administered to Pregnant Sprague Dawley Rats for Technical Training Program

 

P64

McCuistion EA, Bailey M, Emily M. Emporia State University, Emporia, KS, United States. Hemp Oil Does Not Have Adverse Effects on Fetal Development in ICR Mice

 

P65

Quevedo C1, De Croze N2, Alday A1, Muriana A1, Léonard M2. 1Biobide, San Sebastian, Gipuzkoa, Spain, 2L’Oreal, Research & Innovation, Aulnay-sous-Bois, France. Zebrafish and Medaka as Alternative Models for Developmental Toxicity Assessment of Chemicals (Including Behavior As an End Point)

P66

Ttayem YR, Veeramuthu S, Rashid AN, Reginald SP, Fadel RA. Arabian Gulf University, Manama, Bahrain. Effects of Melamine Administration during Pregnancy on Fetal Bone Ossification

 

P67

Wong L, Fullerton A, Halpern W. Genentech, Inc., South San Francisco, CA, United States. Predicting Embryofetal Developmental Toxicity from In Vitro Assays

 

P68

Ceger P1, Bell S1, Choksi N1, Hamm J1, Daniel A1, Allen DG1, Kleinstreuer NC2. 1ILS, Research Triangle Park, NC, United States, 2NIH/NIEHS/DNTP/NICEATM, Research Triangle Park, NC, United States. Application of a Controlled Vocabulary to Curated Databases of In Vivo Developmental Toxicity Data

 

P69

Hootnick DR1,2,3. 1Department of Orthopedic Surgery, SUNY Upstate Medical University, Syracuse, NY, United States, 2Department of Pediatrics, SUNY Upstate Medical University, Syracuse, NY, United States, 3Department of Cellular and Molecular Biology, SUNY Upstate Medical University, Syracuse, NY, United States. Dystrophic Fibula: New Terminology for Absent Fibula

 

P70

Mohamed LM1, Guled IA1, Hassan FA1, Hassan AO1, Faqi AS2. 1Benadir Hospital, Mogadishu, Benadir, Somalia, 2ASF Scientific Solutions, Portage, MI, United States. Cases of Congenital Heart Defects in Benadir Hospital, Mogadishu (Somalia)

 

LB6

Hayatullah G, Han L, Yidan Y. Third Gynecology Department of First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China. Clinical and Pathological Analysis of 21 Cases of Malignant Transformation of Endometriosis

 

LB7

Elizondo-Plazas A, Ibarra-Ramírez m, Calzada-Dávila m, Jasso-Gaona RS, Salazar-Rivera R, Martínez-de-Villarreal LE. University Hospital "Dr. José E. Gonzalez," Universidad Autonoma de nuevo Leon, Monterrey, Nuevo León, Mexico. Increased Frequency of Flow Regression syndrome in a Population of Northeast Mexico

 

LB8

Yao H1, Wu W1, Zhao HW1, Wang J1, Negraes PD1,3, Muotri A1,3,4, HaddadG1,2,4. 1Department of Pediatrics, University of California–San Diego, La Jolla, CA, United States, 2Department of Neuroscience, University of California–San Diego, La Jolla, CA, United States, 3Department of Cellular and Molecular Medicine, Stem Cell Program, University of California–San Diego, La Jolla, CA, United States, 4The Rady Children’s Hospital, San Diego, CA, United States. Methadone Attenuates Neural Network Activity in Human Cortical Organoids

 

LB9

Trujillo CA, Jones KL, Del Campo M, Muotri AR. University of California–San Diego, School of Medicine, Department of Pediatrics, Rady Children's Hospital San Diego, La Jolla, CA, United States. A Human Neurodevelopmental Model of Fetal Alcohol Spectrum Disorders

 

LB10

Laffan SB1, Kohrs L1, Kambara T3, Rambo M1, Roulois A2, Turner S1. 1GlaxoSmithKline, In Vitro In Vivo Translation, Collegeville, PA, United States, 2GlaxoSmithKline, In Vitro In Vivo Translation, Ware, United Kingdom. 3AbbVie, Preclinical Safety, North Chicago, IL, United States. Brain Weight Effect of Ambrisentan in Juvenile Rat Toxicity Study Associated with Breathing Sounds, Apnea, and Sustained Hypoxemia

 


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Organized by the Teratology Society Science Committee
Chairpersons: Nicole Churchill Kleinstreuer, NTP Interagency Center
for the Evaluation of Alternative Toxicological Methods, NIEHS and
Jessica A. Palmer, Stemina Biomarker Discovery, Inc.


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